Noteworthy, Yin et al. [16] and Krüger et al.[12] found that PST2, one of these phage types detected within O157:H7 strains associated with a high incidence of HUS, was closely related to Stx2a phages identified in some non-O157 STEC strains corresponding to serotypes like O103:H2, O104:H4 and O145:H-. This evidence concerns the gene STX2 and hemolytic-uremic syndrome.