There was no statistical evidence that higher concentration levels of IL-2 affected the risk of delirium in either the Suhre et al. dataset (OR = 0.91, 95% CI: 0.76–1.11, P = 0.41) or the Sun et al. dataset (OR = 1.02, 95% CI: 0.89–1.18, P = 0.75) using a significance threshold of a P-value of < 5e-6 (Supplementary Table S5). The gene discussed is IL2; the disease is delirium.