C3 and atherosclerosis: In the atherosclerosis dataset GSE28829, CD14 (AUC = 0.938), C1QB (AUC = 0.947), CD53 (AUC = 0.952), LY96 (AUC = 0.904), P2RX7 (AUC = 0.981), C3 (AUC = 0.817), and TNFSF13B (AUC = 0.875) demonstrated favorable diagnostic efficiency for differentiating patients with atherosclerosis from controls (Figure 6E).