However, in pancreatic tumor cells with a high level of Kindlin-2, Kindlin-2 associated with DDX3X and recruited more DDX3X to the 5'UTR of c-Myc complex structure, thereby promoting translation of c-Myc mRNA, further increasing c-Myc expression to promote tumor cell proliferation (Figure 9J). Here, FERMT2 is linked to pancreatic neoplasm.