Inhibition of GPX4 by siRNA transfection decreased cell viability of A549 and H1975 cells in the MPE of LCP compared with lung cancer cells transfected with control siRNA (Figure 3H and Figure S4H-I), whereas ectopic expression of GPX4 prevented cell death induced by MPE in HCC827 cells (Figure 3I). Here, GPX4 is linked to lung cancer.