ANO5 and gnathodiaphyseal dysplasia: Recently, a missense mutation in ANO5 (also known as TMEM16E) was identified in GDD and was considered a suspected causative mutation for GDD (Duong et al., 2016; Jin et al., 2017; Marconi et al., 2013; Mizuta et al., 2007; Otaify et al., 2018; Tsutsumi et al., 2004; Zeng et al., 2019).