CD8A and cancer: However, immune escape mechanisms can be reversed by cancer immunotherapy, including the use of tumor vaccines to improve antigen presentation, the increase in antitumor T cells by adoptive metastasis of tumor-infiltrating lymphocytes (TILs) and T-cell receptor (TCR)-transduced T cells, the restoration of CD8+ T-cell effector capacity by immune checkpoint blockades (ICBs), and T cells induced by bispecific antibodies (bsAbs) and chimeric antigen receptors (CARs) to increase the immune recognition of tumors [5–7].