Some of the identified dmCpG sites showed association with ever-asthma (cg22402007: NTRK2), ever-wheezing (cg11380624: DNAJC14, cg10981514: TPCN1), weight (cg12053348, cg03380960: FAM53B, cg22402007: NTRK2 [44]) and BMI (cg03380960: FAM53B, cg12053348, cg22402007: NTRK2) at p < 0.05 as shown in (Additional file 1: Table E4). The gene discussed is FAM53B; the disease is asthma.