INS and endometriosis: We further explored whether relevant serum metabolic indexes were involved in endometriosis development via a retrospective study including 412 endometriosis patients and 1551 control patients in the present study and found endometriosis patients present with higher serum levels of INS, TC, HDL-C, LDL-C and lower serum level of basal T. By logistic regression analyses, we developed a model combining the number of previous pregnancies, serum levels of CA125, Glu and INS to predict the occurrence of endometriosis.