We also explored whether the dysregulated metabolic indexes had effects on the number of retrieved oocytes, ART outcome and the incidence of pregnancy complications in endometriosis patients, and we found the number of retrieved oocytes was positively correlated with INS in endometriosis group, while the number of retrieved oocytes was negatively correlated with Glu in control group. The gene discussed is INS; the disease is endometriosis.