However, when they were co-cultured with oe-Fcnb-transfected and BLM-induced AMs, the expressions of cGAS, LC3II/LC3I, Beclin1, and ATG7 were upregulated, and the phosphorylation of STING was also increased, while the expression of p62 was downregulated (Fig. 5A–C). This evidence concerns the gene CGAS and Bloom syndrome.