In addition, re‐transfusion of macrophages infected with Lenti‐shR‐TFRC by tail intravenous injection significantly improved TAC‐induced heart function injury (indicated by decreased LVEDd and increased EF measured by echocardiographic evaluation), compared to re‐transfusion of macrophages infected with Lenti‐shR‐Ctl (Figure 4D,E). The gene discussed is TFRC; the disease is persistent truncus arteriosus.