However, CD4+CD294+ (AUC = 0.569, p = .283), CD4+CD127+ (AUC = 0.604, p = .119) and CD4+FOXP3+ (AUC = 0.615, p = .067) could not significantly predict RA (Figure 4A). This evidence concerns the gene PTGDR2 and rheumatoid arthritis.