However, Suzuki et al. reported that other chemokines receptors such as CCR5 expression was decreased in RA patients compared with healthy controls, and explained that differential expression of chemokine receptors plays a critical role for selective recruitment of pro‐inflammatory T cells into the joints of RA32; which was similar to the results of this study, thus this study is the first to report the low expression of CD4+CD183+ among RA patients in the Ghanaian population. The gene discussed is CD4; the disease is rheumatoid arthritis.