CXCR3 pathway plays a key role in joint inflammation occurring in RA as it has been demonstrated that lipoxygenase, cyclooxygenase and TNF‐α inhibitors which serve as analeptic molecules inhibit the synthesis of CXCR3 ligands by synovial fibroblasts and alter the migration of CXCR3+ T cells.20, 21. This evidence concerns the gene CXCR3 and rheumatoid arthritis.