ALK and non-small cell lung carcinoma: Commonly found to be mutated in NSCLC adenocarcinomasare the epidermal growth factor receptor (EGFR) and the anaplasticlymphoma kinase (ALK).2−4 The most common EGFR mutations found are the tyrosinekinase domain mutations Del19 (deletion in exon 19) and L858R (insertionin exon 21),5−7 resulting in continuous receptor activation independentof ligand interaction.