SPDL1 and invasive carcinoma: First, patients who underwent radical surgery for invasive carcinoma (n = 55) (Supplementary Table 2) were classified into two groups according to preoperative plasma sPD-L1 levels: the high sPD-L1 group (≥ 80 pg/mL) and the low sPD-L1 group (< 80 pg/mL), as described earlier.