F2 and Thrombocytopenia: Kasabach-Merritt phenomenon is characterized by a normal to slightly prolonged prothrombin time and partial thromboplastin time, severe thrombocytopenia, hypofibrinogenemia, and elevated D-dimer, and affects up to 71% of patients with KHE.1,3 When unrecognized or not treated promptly, KMP can cause severe bleeding, disseminated intravascular coagulation (DIC), shock, and multi organ failure.