CEACAM5 and neoplasm: Several reports suggest TSGF as an efficient diagnostic marker for detecting hepatocellular carcinoma since its sensitivity can reach 82% at the cut-off value of 62 U/L.30-32 A simultaneous determination of serum TSGF level and other tumor biomarkers, namely, AFP, CEA, TSA, and ferritin, showcased sensitivity and specificity of 98.4% and 99%, respectively, at the cut-off value of 65U/L32 (Table 1).