Therapeutic choices for SBS patients are growth factors and seven other trophic hormones7 and among them; FDA has approved short-term application of human growth hormone, somatropin and L-glutamine in SBS patients with limited efficacy.5,8 GLP2 is an endogenous throphic peptide which has indispensable activity in improvement of intestinal growth and function. This evidence concerns the gene GCG and macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss.