In 32 different cancers, the IFN-γ score was strongly linked to CD86, CD48, KLRK1, LTA, CD27, TNFSF13B, TNFRSF9, CD40LG, KLRC1, IL2RA, and CD80, out of a total of 46 immune activation genes in pan-cancer (All P < 0. The gene discussed is CD27; the disease is cancer.