The results of the association between IFN-γ score and ICG indicated that the IFN-γ scores of virtually all of the different cancers that were investigated had a positive association with the expression of TIGIT, IDO1, ICOS, CD86, CTLA4, HAVCR2, PDCD1LG2, and CD48 (Figure 11A). This evidence concerns the gene ICOS and cancer.