IL2RG and Immunodeficiency: In 2002-2005,NSG (NOD/LtSz SCID,IL2rg-/-)/NOG(NOD/Shi SCID, IL2rg-/-) (30)mice were generated, which are NOD-SCID mice with IL2rg-/-,not only lacking T,B and NK cells but also complement C5,and showing severe immune deficiency.