KIT and chronic myelogenous leukemia, BCR-ABL1 positive: For example, the exogenous cytokine c-kit ligand can improve the implantation of normal and leukemia CP-CML (chronic phase of chronic myeloid leukemia) cells (143); SCF tg improves the implantation of irradiated NSG HSCs and eliminates radiation-related complications (131, 132),SCF/KIT ligand tg improves the development of human granulocyte lineage and human myeloid lineage (132).