We found nominally significant associations of the predicted damaging CCR2 variants with myocardial infarction (OR: 0.60, 95%CI: 0.40–0.90, p=0.008) and coronary artery disease (OR: 0.76, 95%CI: 0.59–0.99, p=0.03), as well as directionally consistent associations with the odds of all other examined outcomes (ischemic stroke, peripheral artery disease, abdominal aortic aneurysm, Figure 2A). Here, CCR2 is linked to coronary artery disorder.