Bastan et al. demonstrated that puppies with naturally occurring CPV-2 enteritis who died from the disease and had evidence of myocarditis at necropsy had significantly higher cTnI values (cTnI >0.8 ng/ml) compared with the values in dogs who either survived or died but had no cardiac involvement at necropsy (cTnI < 0.156 ng/ml) (36). The gene discussed is TNNI3; the disease is myocarditis.