CTRP1 ↓adhesion molecules expression in ECs, ↓vascular remodelingCTRP3 ↑the activity of eNOS via the AMPK pathway, ↓ECs inflammation via the PI3K/Akt/eNOS pathwayCTRP5 ↑12/15-LOX in ECs via the STAT6 pathwayCTRP9 ↑plaque stabilization, ↓macrophages infiltration in plaque via the AMPK/mTOR pathway↑autophagy in ECs and macrophages, ↓pro-inflammatory phenotype via the JNK pathwayCTRP12 ↓VSMC proliferation via the TGF-βRII/Smad2 pathway↑anti-inflammatory phenotype via the miR-155-5p/LXRα pathwayCTRP12 level is inversely associated with CAD severity, CTRP12 ↑in VAT and SAT of obese subjects. Here, LOX is linked to coronary artery disorder.