<h4>Purpose</h4>Our aim was to conduct a meta-analysis and systematic review in order to compare the diagnostic efficacy of <sup>68</sup>Ga-PSMA-11 PET/CT and <sup>68</sup>Ga-PSMA-11 PET/MRI in patients with biochemically recurrent after radical prostatectomy and biochemically recurrent prostate cancers (BCR) after hybrid RT and RP.<h4>Methods</h4>Up until February 2023, we searched PubMed, Embase, and Web of Science for pertinent papers. The gene discussed is FOLH1; the disease is Familial prostate cancer.