Similarly, the attachment factor B0AT1 (SLC6A19) can enhance the stability of ACE2 and assemble it into a high-quality and stable heterodimer structure, and the ACE2-B0AT1 complex can simultaneously bind two S proteins, significantly promoting SARS-CoV-2 recognition and infection of host cells (Yan et al., 2020). The gene discussed is ACE2; the disease is infection.