The 10 properties assessed in this work included: Caco-2 (the human colon adenocarcinoma cell lines) permeability, F20% (the human oral bioavailability 20%), Pgp-substrate (the substrate of P-glycoprotein), Pgp-inhibitor (the inhibitor of P-glycoprotein), VD (volumn density), T1/2 (The half-life of a drug), FDAMDD (The maximum recommended daily dose), SAS (synthetic accessibility score), log P (the logarithm of the noctanol/water distribution coefficient), and log S (the logarithm of aqueous solubility value). The gene discussed is PGP; the disease is colon adenocarcinoma.