CYP24A1 encodes 24-hydroxylase and its high expression accelerates the inactivation of 1,25(OH)2D. It was reported that CYP24A1 is overexpressed in various human tumors including colorectal cancer, and the alternation of CYP24A1 expression is related to the development of cancer [36–38]. Here, CYP24A1 is linked to cancer.