ROC analysis displayed that serum ITGB2 gene expression was an excellent discriminator of RA patients from healthy controls with an AUC = 0.966, 95% CI = 0.9172 to 1.016, P < 0.0001, with a sensitivity of 93.02% and a specificity of 100% at a cutoff > 3.147-fold (Fig. 5A). Here, ITGB2 is linked to rheumatoid arthritis.