Altogether, it seems bft could be associated with the dysregulation of the WNT/β-catenin pathway, and this pathway must be tightly regulated due to its important physiological role, as its dysregulation, which is brought on by B. fragilis, may alter cell proliferation, apoptosis, and inflammation-related CRC [20, 50, 51]. The gene discussed is PITX1; the disease is colorectal carcinoma.