The ROC curve also indicated that the combination of PDCD1 and ICAM1 could predict unfavorable prognosis of LGI1 encephalitis patients at one-year follow-up more accurately than either PDCD1 or ICAM1 alone (AUC = 0.936 p = 0.003 vs. AUC = 0.821 p = 0.028; AUC = 0.778 p = 0.052) (Fig. 3K–M). This evidence concerns the gene ICAM1 and viral encephalitis.