Our in vitro experiment elucidated that higher expression of miR-2467-5p in PBMCs not only significantly induced silence of PDCD1 and CSF3 expression but enhanced CCL15 activation, and this phenomenon was also consistent with our findings that miR-2467-5p expression in PBMCs of LGI1 encephalitis patients was negatively correlated with the expression of PDCD1 and CSF3 in serum while positively correlated with CCL15 expression in serum. The gene discussed is CSF3; the disease is viral encephalitis.