Anti-LGI1 encephalitis is strongly associated with genetic risk factors, including human leukocyte antigen (HLA) alleles DRB1*07:01 and DRB1*04:02 haplotypes in Whites and Asians, and DRB1*03:01 in Chinese anti-LGI1 cases [6, 7]. The gene discussed is LGI1; the disease is viral encephalitis.