TNF and asthma: In terms of inflammatory cytokines, ATG5 was positively associated with TNF-α (rs=0.247, P < 0.001) (Fig. 4A), IL-1β (rs=0.233, P = 0.001) (Fig. 4B), IL-6 (rs=0.213, P = 0.003) (Fig. 4C), and IL-17 (rs=0.154, P = 0.029) (Fig. 4D) in adult asthma patients.