When comparing median baseline protein levels between MS and controls, 6 proteins demonstrated a difference that was statistically significantly (Mann-Whitney U, p < 0.05) (Fig. 2) (Mann-Whitney U, p-value; CAMK2A p = 0.0476, CNTNAP4 p = 0.0298, IGLON5 p = 0.0434, RTN4RL2 p = 0.0396, SEZ6L p = 0.0396, TMEM132D p = 0.0197). Here, TMEM132D is linked to myeloid sarcoma.