CXCR4 and ovarian cancer: The results showed that similar to the stimulation of ovarian cancer organoids, the proportions of CD11b+, CD66b+, and ICAM-1+ neutrophils in each case of neutrophils were significantly increased after MUC16 treatment for 24 h, while the proportions of CXCR4+ neutrophils were decreased slightly (Fig. 3B).