LPL and hypertriglyceridemia: Adiposity was known to impair lipolysis of TG-rich lipoproteins by reducing the lipoprotein lipase expression in adipose tissue [56], hypertriglyceridemia correlate with the formation of small dense of LDL [57] and the dissociation of cholesterol esters from HDL [58], ultimately lead to higher levels of LDL and lower levels of HDL.