A DCIS (HER2 positive, hormone receptor positive) with BI-RADS 4a category by standard breast US showed false-negative 2D SWE (Emean < 90 kPa) and true-positive 2D + 3D SWE (Emean > 90 kPa) (Fig. 5). Here, ERBB2 is linked to ductal breast carcinoma in situ.