PTPN11 and cryopyrin-associated periodic syndrome: The expression level of ITGB7, CD68, ITGAE, IL10, ITGAL, ITGA4, CD4, CD1C, PTPRC, CD163, TNF, BTK, CD86, MRC1, LYN, and CD80 was higher, and the expression level of PTPN11, JAM3, ITGA8, and ITGA9 was lower in patients with CAPs (Fig. 5A).