For evaluating the efficacy of viral infection, an assay was developed to measure cell entry by the pseudoviral particle (Vpp) of SARS-Co-V-2, entailing the mammalian cell lines 293T-ACE2 (human embryonic kidney cells expressing ACE2) and NCI-H460 (human non-small cell lung cancer cells). This evidence concerns the gene ACE2 and viral infectious disease.