Second, we orthotopically transplanted human MDA-MB-468 breast cancer cells expressing either Akaluc or MYC-P2A-Akaluc into the mammary glands of immunocompromised NOD-Prkdcscid-IL2rgTm1/Rj (NXG) female mice via intraductal injection. This evidence concerns the gene MYC and breast carcinoma.