On univariate logistic regression analysis male sex, age, cardiac disease, COPD/asthma, diabetes, morbid obesity, hypertension, immune deficiency, chronic liver disease, chronic kidney disease, neuromuscular disease, malignancy, SAPS3 (excluding age and comorbidity components) and admission period were significantly associated with mortality. The gene discussed is PPP6R3; the disease is neuromuscular disease.