FOSL1 and central nervous system cancer: In addition, we previously reported that TRPM7 enhances GSC stemness by regulating the established GSC marker ALDH1 and promotes the induction of ALDH1 activity in glioma cells [2]; therefore, we further tested the relationship between FOSL1 and GSC stemness markers TRPM7 and ALDH1 by IHC assay.