CAV1 and central nervous system cancer: The differential CAV1 mRNA expression between tumor and adjacent tissues were shown in Fig. 1A. CAV1 mRNA expression was significantly higher in low-grade glioma (LGG) (Fig. 1B), the combination of LGG and glioblastoma multiforme (GBMLGG) (Fig. 1C) as well as glioblastoma multiforme (GBM) (Fig. 1D), compared with adjacent tissues.