Immunohistochemical staining of normal cervical tissues and cervical cancer tissues showed that ADAMTS12 was mainly expressed in the cytoplasm (Fig. 1C), and the expression of ADAMTS12 in cancer tissues was apparently higher than that in normal cervical tissues (quantified in Fig. 1D).We prepared cervical cancer tissue microarrays, which included 382 cases, detected the expression of ADAMTS12 in tumor tissues by immunohistochemistry, analyzed the correlation between ADAMTS12 expression and clinicopathological features. Here, ADAMTS12 is linked to cancer.