However, our tissue chip analysis showed that DEPDC1B expression was only correlated with lymph node metastasis (χ2 = 9.098, P = 0.028) (Table 1, Fig. 3D) and positively correlated with poor prognosis (χ2 = 5.487, P = 0.019) (Table 1) and resulted in poor OS (Fig. 3C). This evidence concerns the gene DEPDC1B and metastatic malignant neoplasm in the lymph nodes.