Dong et al. [183] demonstrated the serum-derived exosomal-eIF4E in NSCLC individuals to be notably higher compared to healthy individuals suggesting that augmented levels of exosomal eIF4E in NSCLC tissues were associated with advanced TNM stage, distant metastasis and late-stage disease, consequently leading to poor survival. The gene discussed is EIF4E; the disease is non-small cell lung carcinoma.