They reported that patients who were initially suspected of having lung cancer but were later found to be cancer-free had elevated levels of leucine-rich alpha-2-glycoprotein (LRG1) in urine-derived exosomes when compared to controls indicating that LRG1 obtained from urine might be a feasible non-invasive biomarker for diagnosing NSCLC [7]. The gene discussed is LRG1; the disease is cancer.