Additionally, ESCC ATLAS catalogs a study that suggests SASH1 is downregulated in the Chinese population as well in the onset of ESCC [37],—BLNK (B Cell Linker is a leukocyte protein that contains SH2 domain) that is known to produce B-cell linker protein crucial for B-cell development [38]. This evidence concerns the gene PROS1 and esophageal squamous cell carcinoma.