CD4 and hepatocellular carcinoma: When we removed CD4+ T cells during HCC induction using anti-CD4 (Fig. 6g and Extended Data Fig. 8g), we observed that CD4+ T cell depletion did not affect HCC progression in Chatfl/fl mice but tended to reduce it in Chatfl/fl; Cd4-cre mice (Fig. 6h,i).