Although there is no report of EGCG improving coronary microcirculation by treating coronary microembolism, other flavonoids such as curcumin (CCM) have been shown to inhibit CME-induced myocardial inflammation and cardiomyocyte apoptosis through the TLR4/MyD88/NF-kβ signaling axis79, implying that EGCG may also have the potential of improving coronary microcirculation, but the specific research still needs to be further studied. The gene discussed is TLR4; the disease is myocarditis.