The IHC grade scoring system for the Akt gene showed that the median grade was 3 (2‒3) for CRC, 4 (3.5‒4) for PC, 4 (3.5‒4) for LVM, and 1 (1‒1) for normal tissue (p < 0.001). Here, AKT1 is linked to colorectal carcinoma.