The zebrafish xenograft model has been developed as an ideal tool to observe tumor cell proliferation and metastasis, which has the intrinsic advantages of scale, cost, time, and multiplexing of conditions compared with 2D cultures.22 In this context, zebrafish larvae were chosen to investigate the effect of MALAT1 on HPV-positive cervical cancer in vivo. This evidence concerns the gene MALAT1 and cervical carcinoma.