Followed by flow cytometric verification, the CD3+ CD8+ lymphocyte population was expanded into the dominant subgroup of the lymphocyte population and incubated with untreated and treated LNCaP cells (a model for castration‐sensitive PCa) or C4‐2 human PCa cell line (a cell model system for CRPC). The gene discussed is CD8A; the disease is posterior cortical atrophy.