In a prediction study of a cohort of 275 MM patients, a six parameters prognostic model, including ApoB, apoa1, LDL, HDL and TG, was capable of stratifying patients into high- and low-risk groups and predicting survival with greater accuracy and discriminatory ability than conventional (ISS and Durie Salmon) staging systems. Here, APOA1 is linked to Miyoshi myopathy.